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Receptor Activity and Approval Status Is petrelintide a selective AMY1 agonist

Also referred to as thymic polypeptide extract, this complex comprises a mixture of peptides spanning an approximate molecular weight range of 1000 to 3000 g/mol

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10.1126/scitranslmed.adn3079 63 KopanR.IlaganM

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The compounds used in the initial screen comprise the Prestwick Chemical Library (Prestwick-Chemical, Illkirch Graffenstaden, France) 1280 Drug Collection, Repurposing collection (4479 compounds in preclinical, phases 1, 2 and 3 of clinical studies and approved from different suppliers mainly MedChem Express and Tocris Bioscience ) and anticancer drugs plate (the 71 anticancer drug compounds used in the clinic were purchased from different suppliers including Acros Organics , MedChem Express , and Cayman Chemicals )