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Competing interests The funder had no role in study design, data collection, and analysis, decision to publish, or preparation of the manuscript

Several GPs that showed significant fold changes in subjects with metabolic syndrome had also shown similar changes (e.g., increase or decrease) at the end of 4th week during 30-day intermittent fasting (KIT, CROCC, DNTT, POLK, SRGN, CLSTN1) and 1 week after 30-day intermittent fasting (PRKCSH, CALU, SPECC1L, IGFBP4, MYH7, CDH6, H2B histone, PKP1, LRRC3, FGB, ENPP2) in our previous study conducted in healthy subjects although they had not reached statistical significance 15