l carnitine cell culture SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo biosynthesis: Molecular L-Carnitine tartrate | β-Oxidation Cofactor

compared healthy (high-fiber) and unhealthy (high-cholinergic) diets and found that the TMAO produced by the diet is only partially related to the degree of atherosclerosis, because a high-cholinergic diet may work through a series of pro-inflammatory and platelet activations, rather than single mediators ( ApoE / mice ( Table 2 The positive or non-effects of trimethylamine-N-oxide (TMAO) on atherosclerosis demonstrated via clinical and non-clinical experiments

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Experimental evidence suggests that the transport of long chain fatty acids into the mitochondria is a rate limiting step in fatty acid oxidation

PMID 12908852

Enfin concernant les effets secondaires, la prise de la L-Carnitine rgulire et longue dure ne pose pas de problmes particuliers, mais peut provoquer dans certains cas des nauses, vomissements, maux destomac, brlures destomac, diarrhe

Early intervention gives you the best chance at avoiding surgery