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Due to the evidently good predictivity of the in vivo alkaline comet assay, it seemed worthwhile to also evaluate the in vitro alkaline comet assay regarding its potential to detect mutagenic/carcinogenic NAs, when performed with relevant, metabolically competent mammalian tissue or cell types

Biochemistry of B12-cofactors in human metabolism

Weekly injections could work, but we need to explore simpler options, like a food additive or ointment, said Le Poole

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the membrane potential was held at -70 mV at room temperature (25C) during a period of 0.5-2 h after removal of the culture from the incubator