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89 COMPARISON OF RECURRENCE PREDICTION MODELS AND IMBRAVE 050 CRITERIA TO SELECT PATIENTS FOR ADJUVANT IMMUNOTHERAPY AFTER CURATIVE RESECTION OF HEPATOCELLULAR CARCINOMA I-Cheng Lee 1,2 , Hao-Cyuan Chu 2 , Shinn-Ying Ho 2 , Gar-Yang Chau 3 , Ming-Chih Hou 1 and Yi-Hsiang Huang 1,2 , (1)Taipei Veterans General Hospital, (2)National Yang Ming Chiao Tung University, (3)Taipei Veterans General Hospital Department Surgery Background: The IMbrave 050 trial recently demonstrated positive results of the adjuvant atezolizumab plus bevacizumab therapy for hepatocellular carcinoma (HCC) patients at high-risk of recurrence after curative treatment

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Overall, the elongated ASXL1 EBM -binding groove, delineated by I622, L630, V633, V634, I652, I654 and F656 of BRD4 ET , is mainly hydrophobic but is surrounded by the negatively charged walls created by the residues of the 1 strand and the 2-3 loop of BRD4 ET , such as D650, E651, E653, D655 and E657 (Fig