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2015;104(2):426-34.e1

At the start of the experiment, each mouse was placed in a dedicated chamber for continuous monitoring

Key similarities: Negative charge Involved in protein interactions Difference: Glutamic acid has one extra carbon in its side chain

468 Hyperactivation of mTORC1 reduces the autophagic clearance of amyloid-beta, promoting its accumulation in the brain

Forsberg et al., Integrin receptors Integrin receptors are large transmembrane glycoproteins that are made up of non-covalently associated and subunits and are present in virtually all mammalian cells (Harburger and Calderwood, 2009

Free water imaging, calculated from diffusion weighted MRI, separating the diffusion properties within tissue from those in the extracellular space, can also be used as a measure of SN dopaminergic neuronal degeneration in PD, where increases in extracellular space correspond to loss of neurons 51