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Human trial results were more modest

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High-dose oral therapy (1000 micrograms daily) can be effective even in some malabsorption states due to passive diffusion mechanisms, though this is not standard first-line practice in the UK and should follow local policy

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[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Jendricke P, Kohl J, Centner C, Gollhofer A, Knig D

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