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This metabolic shift is responsible for metformins well-established ability to suppress hepatic gluconeogenesis and increase glucose uptake in peripheral tissues, like skeletal muscle

Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line

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However, previous research in animal models of ASD has shown increased glutamate receptor binding during adolescence instead of childhood, potentially reflecting compensatory mechanisms for earlier synaptic alterations [60]

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