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PLoS One , 8 , e79873 Adlouni, A., Ghalim, N., Saile, R., Hda, N., Parra, H

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First, GSH is vital for normal cellular functions, including detoxification and protection against oxidative stress, so systemic depletion can damage healthy tissues such as the liver, kidneys, and bone marrow

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Since oxidative stress increases the heterogeneity of the RBCs population, the hematological parameter RDW might be preferable for detection and analysis of damaging levels of oxidizing agents and deterioration of microcirculation than MCV

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