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Factors that Affect How Long Alcohol Stays in Your System There are a number of factors that can affect how long it takes for alcohol to leave your system, including: Your weight and body mass Your gender How much alcohol you've consumed How quickly you've consumed the alcohol Whether you've eaten recently Your overall health and metabolism How Long Does Alcohol Stay in Your System

This is also consistent with the fact that metformins primary beneficial effect in type 2 diabetes is in the intestines [30]