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Results Study population Of 974 ART-experienced adults with HIV in OPERA who switched to a DOR-containing regimen for the first time between 30AUG2018 and 30NOV2022, 388 met all inclusion criteria for the study (Fig

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Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs

Mammalian Sirt1: Insights on its biological functions

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Insulin-like growth factor I and growth hormone (GH) treatment in GH-deficient humans: differential effects on protein, glucose, lipid, and calcium metabolism