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*Correspondence: Yi Hua, [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

This is particularly crucial in highly secretory cells such as pancreatic -cells, where efficient insulin production depends on intact Golgi dynamics

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in the skeletal muscle, insulin promotes the utilization and storage of glucose by increasing glucose transport and net glycogen synthesis

Analysis of transcriptional activation of gst-4 is often used as a proxy for oxidative stress tolerance 46