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Abbreviations ApoB: Apolipoprotein B-100 ApoC1: Apolipoprotein C1 ApoM: Apolipoprotein M FDR: False discovery rate GPX3: Glutathione peroxidase 3 HGFAC: Hepatocyte growth factor activator INNODIA: Innovative approaches to understanding and arresting type 1 diabetes LMM: Linear mixed model ND: Newly diagnosed SRM: Selected reaction monitoring UFM: Unaffected family member References Fyvie MJ, Gillespie KM (2023) The importance of biomarker development for monitoring type 1 diabetes progression rate and therapeutic responsiveness

Terry JL, Milovancev M, Lhr CV, Nemanic S (2016): Changes in the dimension and volume of feline injection-site sarcomas following formalin fixation as determined by use of the ellipsoid volume formula and three-dimensional computed tomography software

Effect of berberine Phytosome on reproductive, dermatologic, and metabolic characteristics in women with polycystic ovary syndrome: a controlled, randomized, multi-centric, open-label clinical trial

These remaining data (12,500 chemicals) were randomly divided into 80% training set, and 20% validation set

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