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Interestingly, recent studies have shown that extracellular Glu can stimulate Ca 2+ release from the astrocytic intracellular stores, further triggering Glu release from astrocytes to the adjacent neurons via an exocytotic mechanism (Mahmoud et al., 2019)

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It is also used also to manage alcohol dependence

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If its used for a medical procedure, it wont cause lasting effects but if its frequently used recreationally, it can seriously affect B12 levels, cause a deficiency and impair healthy functioning of the body (Campdesuner et al., 2020