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Data availability The metabolomic MS raw data have been deposited to MetaboLights with the dataset identifier MTBLS13900

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Before incubation with the primary antibody, lipid droplets in bovine oocytes were cleared with 4,000 U/ml lipase from Candida rugose (Thermo Fisher Scientific) in 400 mM NaCl, 50 mM Tris (pH 7.2), 5 mM CaCl 2 , and 0.2% sodium taurocholate supplemented with ethylenediaminetetraacetic acid-free Protease Inhibitor Cocktail (11,836,170,001

This research convincingly shows the ability of gene down-regulation to enhance disease resistance in plants, like RNAi-mediated oncogene silencing can be used to manage crown gall disease [59]

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Cancer 57 , 395402 (1988)