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Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man

Morphine-6-glucuronide is pcol active N-acetyl procainamide is pcol active GSH conjugates of haloalkenes are nephrotoxic via -lyase Acyl glucuronides are reactive, binding covalently to proteins Of 52 pcol active metabolites in a 1985 review, only two were conjugates and those were acetylated products (Sutfin and Jusko, in Drug Metabolism and Disposition: Considerations in Clinical Pharmacology, Wilkinson and Rawlins, ed

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At 4 h post-second thymidine release (mid-S phase), cells were fixed with 4% paraformaldehyde (PFA), and nuclei were counterstained with DAPI

Feb 3 2014;124(2):617-630

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