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Oxidatieve stress ontstaat wanneer de productie van vrije radicalen de capaciteit van het antioxidant systeem overtreft, wat leidt tot de schadelijke effecten van deze radicalen

[16] [17] Awareness of this risk is essential for both patients and their healthcare teams from the outset

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Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress

Loss of Parkinsons disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c

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