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(PubMed) Weingarten M, Payson B

However, more research is needed to confirm its effectiveness as a treatment for hyperthyroidism

doi: 10.1073/pnas.081082098 5 DeLeveL

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Importantly, the observed phenotype agreed with the hypothesized function of the targeted genes: in the case of feeding of dsDvSnf7, belonging to the ESCRT-III complex involved in vesicle trafficking, impairment of autophagy, accumulation of ubiquitinated proteins, disruption of acidic lysosomal activity and de-stabilization of membranes is observed, all contributing to the induction of lethality (106, 107)