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It operates as a potent antioxidant, scavenging free radicals before they can damage cellular components like DNA, proteins, and cell membranes

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similarly, diminished protein levels of SOD2 were reported in HepG2 cells treated with oleic acid (Sharma et al

Other oncogenes, such as NF-B, MYC, and PI3K, are known to produce ROS, leading to heightened levels of oxidative DNA damage in cells expressing these genes

J The expression of several key ferroptosis regulators, such as FLT, HMOX-1, GPX4, SLC40A1, SLC7A11, was examined by WB in H1299 cells

The N-terminal propeptide serves as the recognition element that leads to the conversion of some glutamic acid residues (corresponding to amino acids 6, 7, 14, 16, 19, 20, 25, 26, 29, 32, and 39 of the FX polypeptide shown in SEQ ID NO: 134)) Y-carboxyglutamic acid (Gla) by the vitamin K-dependent carboxylase (Furie and Furie (1988) Cell, 53: 505-518)