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Current findings related to 13 natural products are summarized in Supplementary Appendix 2

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Both trials employed a Mexameter MX 18 (Courage+Khazaka electronic GmbH, Cologne, Germany) to evaluate the primary efficacy outcome

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This work highlights enzymatic production is inducible and robust in select tissues, whereas iron-catalyzed production contributes underappreciated basal H 2 S systemically with pathophysiological implications in hemolytic, iron overload, and hemorrhagic disorders