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The animal findings on dopamine system preservation are intriguing given the aging-related decline in dopaminergic tone that contributes to motor and motivational deficits in older adults, but this application should be considered speculative pending human data

doi: 10.1007/s11912-020-0885-0 103 TsayJYangZRossFPCunningham-RundlesSLinHColemanRet al

However, there is still a gap between the basic research and clinical application of SFN

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