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GHK-Cu downregulates acute-phase and pro-inflammatory cytokines (TNF-?, IL-6), upregulates anti-oxidant defenses (including superoxide dismutase, Nrf2 and HO-1 pathways), and suppresses fibrotic signaling by inhibiting TGF-?1/Smad2/3 activation

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Walker TA, Jonak ZL, Worsham LMS, Ernst-Fonberg ML: Kinetic studies of the fatty acid synthetase multienzyme complex from Euglena gracilis variety bacillaris

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The 14-day stability window is a reasonable conservative estimate for refrigerated, reconstituted GSH in plain bacteriostatic water, though formal stability data in compounded injectable vials is limited in the published literature