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Consequently, Nb1053 has been radiolabeled with 18 F, resulting in a radioconjugate excreted via the hepatobiliary system, that prevents renal accumulation without compromising tumor uptake [99,100,101,102,103,104,105,106,107,108,109]

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The rationale for combining them is based on mechanistic complementarity (non-overlapping pathways), individual safety profiles, and clinical observations from practitioners administering the combination

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