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Answer: The gut hosts a large share of the body's immune tissue, so when the intestinal barrier is compromised the resulting inflammation can show up far from the digestive tract, in joints, skin, energy, and cognition

The symptoms of EDS vary depending on the specific type, but some common signs include: Overly flexible joints that may dislocate easily Stretchy, soft, and velvety skin Fragile skin that bruises and scars easily Chronic joint pain and fatigue Digestive issues, such as bloating and constipation Dental problems, including tooth crowding and gum bleeding EDS is a genetic disorder caused by mutations in the genes responsible for collagen production

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doi:10.23736/S0391-1977.20.03362-3