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Sharifi-RadMKumarNVAZuccaPVaroniEMDiniLPanzariniEet alLifestyle, oxidative stress, and antioxidants: back and forth in the pathophysiology of chronic diseases

Perspectives series: host/pathogen interactions

Arteel GE, Mostert V, Oubrahim H, Briviba K, Abel J, Sies H

So if you have a gene mutation where your need for glutathione is extremely high, right

Extensive persistent inflammation even when SARS-CoV-2-infected cells are only sporadically present at late stages of COVID-19 (Schurink et al., 2020) could also justify low GSH levels in association with over-abundance of cellular ROS, cellular oxidative damage, increased inflammation and cell death pathways activation seen in inflammaging (Zuo et al., 2019

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