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Moreover, the cytotoxicity studies provide compelling evidence of the biocompatibility of the nanocarrier without ENZ and its potent anticancer activity when loaded with ENZ

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This suggests the essential role of the p53/TIGAR axis in mediating the effects of UA, leading to a reduction in glycolytic potential

Jun 30 2012;147(3-4):136-46

Animal experiments have also shown that PTH improves knee osteoarthritis in rats through autophagy [66]

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Moreover, another critical challenge for clinical translation is the lack of standardized biomarkers to reliably monitor ferroptosis inhibition in patients