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In the STEP 1 trial with 1,961 participants, patients taking 2.4 mg semaglutide weekly alongside reduced caloric intake and increased physical activity lost an average of 14.9% of their body weight over 68 weeks

age was calculated for the treatment group, and found to be r = - 0.20 (not significant)

Any dosing or handling figures refer to laboratory research settings only

This may partly because SGLT2i users at baseline were few (15.6%) and renal events occurred later than MACE in the FLOW

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