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The SPIONs alone had a T2 relaxivity of 137 mM 1 s 1 , while the cluster of SPIONs inside the SPION-QCT micelles had a T2 relaxivity value of about 246 mM 1 s 1 , implying a higher sensitivity for magnetic resonance imaging

GPx has eight isoforms identified as selenoproteins with a selenocysteine in the catalytic center (GPx1-4 and 6) or nonselenoproteins (GPx 5, 7, and 8) [38]

In addition, arginine-capped manganese silicate nanobubbles (AMSNs) are nano-iron inducers that accelerate the depletion of GSH and cause the inactivation of GPX4, thereby inducing ferroptosis in cancer cells [298]

Metformin treatment decreased the abundance of species of Bacteroides fragilis and its bile salt hydrolase activity in the intestines of individuals with T2D, increasing the levels of the bile acid glycoursodeoxycholic acid to inhibit intestinal FXR signaling (47)