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doi:10.1177/17448069211012833

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Headaches Headaches are another common sign of low vitamin B12 levels

Insulin Insulin, a major negative regulator of adipocyte lipolysis, binds the insulin receptor (IR) and through the docking protein insulin receptor substrate 1 (IRS1) and IRS2 (116), activates the lipid kinase phosphatidylinositol 3-kinase (PI3-K), increasing production of PIP3 which stimulates the serine threonine kinase AKT/Protein kinase B (117) (Figure 2)

The peptides influence on neurotransmitters such as 5-HT, glutamate, dopamine, and melatonin is assessed

[DOI] [PubMed] [Google Scholar] 181.Mogensen C.S., Magkos F., Zingenberg H., Geiker N.R.W