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The researcher who has led most of this work is Dr

In contrast, SOCS3, which has been shown to be increased in DCs by tumor-derived substances, interacts with PKM2, resulting in decreased ATP generation under hypoxic conditions and a profound effect on the function of DCs (61)

While this unidirectional behavior effectively destroys cell metabolism for tumor suppression, it poses challenges because of the absence of coupling between the intracellular nanostructures and endogenous feedback mechanisms, thereby hindering their translation to scenarios requiring sustained cellular viability and precise, nondestructive function modulation, including probiotic interventions 46 , programmable cell-based therapeutics 47 and engineered living materials 48

International journal of endocrinology, 201

Targeted therapy of metabolic pathways SCFAs are the primary metabolic products produced by gut microbiota through the fermentation of dietary fibers, with acetate, propionate, and butyrate being the most critical

CNS was found to mitigate inflammation, lower ferroptosis levels, prevent microglial polarization to the M1 phenotype and promote overall mental health (Zhou et al., 2024)