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Research in clinical settings has suggested that exposure to Ipamorelin may cause notable increases in hGH synthesis by these pituitary cells

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This study utilizes a two-hit induced HFpEF mouse model, which closely replicates the key characteristics of human HFpEF

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The primary degradation pathways for both include deamidation and oxidation (particularly of His and Trp residues)

Data availability The RNA-seq data generated in this study have been deposited at Gene Expression Omnibus (GEO) database under accession code GSE280421