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Glutathione protects against infections by enhancing immune cells' ability to recognise and eliminate pathogens such as bacteria, viruses, and fungi

Cells were then transfected with either the pcDNA3 vector (Invitrogen, Waltham, MA, USA) alone as a negative control or with GSK3 or DYRK1A cDNA using JetOptimus transfection reagent (Polyplus transfection, Illkirch, France) following the manufacturers instructions

GSH is a necessary small-molecule cofactor for PrfA, which is directly charged with the transcription of 10 essential virulence factors and has an indirect impact on the expression of over 140 other genes in L

Statistical analysis GraphPad Prism (9.0.0) was used for data analysis

65,66 Notably, molecular changes exhibited by non-proliferative reactive astrocytes can be fully reversible over time after single exposures for example to neuroinflammation caused by LPS

HEV infection can cause fulminant hepatitis failure, especially in pregnant women, with a mortality rate of up to 30%, and the virus can be vertically transmitted from infected mothers to their infants [106]