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There is a slightly higher incidence of ALS among those who served in the military and athletes who played football or soccer, says Catherine Lomen-Hoerth, MD, PhD, FAAN, a neurologist and director of the ALS Center at the University of California San Francisco Medical Center

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A number of studies have evaluated B12, folic acid, and B6 as part of homocysteine-lowering therapy

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Since your body only absorbs what you need, vitamin B12 does not have an upper limit (UL) which is the maximum amount of a vitamin you can take without side effects

While anyone can develop B12 deficiency, certain groups are more vulnerable: Vegetarians and vegans Adults over 50 Individuals with gastrointestinal disorders People taking long-term acid-reducing medications Those who have undergone gastric surgery According to the National Center for Biotechnology Information, vitamin B12 deficiency can result from both dietary insufficiency and impaired absorption, particularly in individuals with underlying gastrointestinal conditions