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On the other hand, the p75 NTR receptor has been reported to either induce or prevent apoptosis upon oxidative insult in both in vivo and in vitro models

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108 To counteract the detrimental effects of oxidants, cells can heighten the production of reducing equivalents such as NADPH

Wang Z, Navarro Poupard MF, Mohan RR, Boddapati L, Zhang J, Kamali S, Biz C, Fianchini M, Deepak FL, Gracia J, Salonen LM, Kolen'ko YV