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Research by Jakhmola et al (147) revealed the significant role of EGFR in ovarian cancer through computational simulation methods and pointed out that the DADETL segment (including the self-phosphorylated tyrosine 992) is the key region leading to receptor overexpression

Platelets and Alzheimer's disease: potential of APP as a biomarker

Among the potential therapeutic approaches, interventions targeting endothelial dysfunction (such as RAAS modulators, and flavonoids) and persistent inflammation (e.g., antioxidants, vitamin C, vitamin D, and AMPK activators like metformin) appear particularly promising

This reasoning was proved experimentally [57]

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Erk phosphorylation was assessed in 50 g HepG2 extracts run on 10% gels and transferred onto a PDVF membrane