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When these pathways are disrupted such that total cellular iron levels rise, the pro-oxidant environment induces excessive lipid peroxidation, most notably of the fatty acyl moieties on phospholipids of poly unsaturated fats, resulting plasma membrane permeabilization and lytic cell death (150)

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In summary, we identify dysregulated pathways and genes in each transgenic fish carrying LMNA variants and disclose their influence on physiological systems

Wahida A, Conrad M

Researchers may also examine its association with detoxification mechanisms, reactive species neutralization, and signaling coordination under controlled in vitro conditions