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Moreover, the PPAR signalling pathway was stimulated by didymin, resulting in the upregulation of PPAR- and RXRA expression in vitro

Baek G, et al

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indeed implicate brain PPAR 2 among the mechanisms by which the KD reduces seizures ( in vivo treatment of rats with a KD increased hippocampal catalase mRNA and protein and that this upregulation required PPAR 2 ( PPAR 2 activation and that catalase may contribute to the antiseizure efficacy of the KD

COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status