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119 , 45924596 (2003) Bastolla, U., Porto, M., Ortz, A.R.: Local interactions in protein folding determined through an inverse folding model

These illnesses include asthma, colitis, and osteoarthritis

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Ferroptosis-related proteins such as ACSL4, SLC7A11, and FTH1 are also differentially expressed

From a clinical perspective, it suggests that in disease states with high IL-5 (like hypereosinophilic syndromes or active IBD with a type 2 skew), targeting Siglec-8 could be especially effective in depleting pathogenic eosinophils