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Maximal flow is typically achieved by challenge with an endothelium-independent vasodilator such as adenosine, dipyridamole, or regadenoson, although follow-up measurement using endothelium-dependent acetylcholine-mediated vasodilation has recently been shown to provide additive prognostic value (Rahman et al., 2020)

& Avoli, M

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Tissue fractions were determined by using FSL anatomical processing script fsl_anat and automated tissue segmentation (FSL v6.0 FAST 63 ) with 5 mm Full-Width Half Maximum bias field correction