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Cationic surfaces and high-generation amine-terminated dendrimers increase membrane disruption, complement activation, and pro-inflammatory cytokine production in vitro and in vivo , whereas neutral or anionic surface chemistries show substantially lower acute toxicity (167, 168)

When administered under professional supervision, this treatment is generally well tolerated and considered safe for most individuals

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For newly released products, COA documentation is being updated and will be made available shortly as part of our ongoing batch verification process