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Honestly, there are compelling arguments on both sides, and the 'right' answer often depends on the specific protocol and research objectives

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It upregulates angiogenic signaling in endothelial models through increased VEGF and VEGFR2 activity

doi: 10.1002/1873-3468.14021 23

Ethics declarations Competing interests Ashley Bush is an Associate Editor of Signal Transduction and Targeted Therapy, but he has not been involved in the process of the manuscript handling