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Notably, lithium, the mood-stabiliser and frontline treatment for bipolar disorder, increases CaMKK2 activity by blocking GSK3-mediated phosphorylation of the S3-node [33]

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Raji cells (human male) were maintained in RPMI + 10% FBS, 2 mM L-glutamine, 100 U/ml penicillin, and 100 g/ml streptomycin (cRPMI)