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Description

Neuroprotective mechanisms of curcumin against cerebral ischemia-induced neuronal apoptosis and behavioral deficits

W., & Phang, J

2004 Dec;44(4):411-6

Despite being the basis of HCU management, conventional therapies have non-negligible limitations, including variability in patient responsiveness to B6

Correspondingly, caspase-3 (pro-apoptotic proteins) activity in -viniferin-treated hepatocytes was measured at only 7.1% following 24 h exposure, compared with significantly higher activation in untreated or vincristine-only groups, demonstrating effective inhibition of the execution phase of apoptosis

Following a detailed analysis of the advantages and challenges associated with nose-to-brain drug delivery, we consolidate recent advances in nasal nano-delivery systems for CNS therapeutics