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Clonogenic survival assays comparing the response to radiation in SCC-61, rSCC-61 and rSCC-61 with MTHFD2 knockdown further confirmed the function of this enzyme in the radiation resistance phenotype of rSCC-61 ( Figure 3C )

A., Gallego, J., Evrard, P

Another curative function of the HO-1 is to facilitate the conversion of heme into BV, Fe 2+ and CO in equimolar quantities, thus promoting efficient antioxidant and anti-inflammatory effects [50]

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3.3.5 Microbiota-based interventions 3.3.5.1 Psychobiotics Psychobiotic interventions targeting the MGBA show promise for reversing stress-induced behavioral and physiological dysfunctions

This increased SF penetration was not reduced in the free-ibuprofen and the non-targeted nanocarrier groups, only the 3-PLG-ibu-A-GSH treatment decreased the elevated permeability in a statistically significant way (Fig