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valproic acid A61K31/195Carboxylic acids, e.g

, Lucas, R

USA 114 , E3324E3333 (2017)

Indeed, most of the autophagosomes generated in axonal terminal regions quickly acquire late endosomal markers (for example, RAB7), which engage the dynein complex and accelerate their retrograde transport to the soma 17

Total cellular proteins were extracted from cultured cells using a RIPA lysis buffer supplemented with phosphatase and protease inhibitors (Roche, Basel, Switzerland)