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Further studies linked the susceptibility to viral-induced myocarditis with a deficiency of GPx1, as GPx1 knockout (GPx1 / ) mice on a normal selenium diet were susceptible to viral-mediated myocarditis whereas wildtype (GPx1 +/+ ) mice were protected from viral-induced cardiac damage [28]

In addition, these investigations predominantly focused on the GBM subtype of brain cancer, thereby restricting the extrapolation of their findings to other histological subtypes