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By attenuating NNMT activity, 5Amino1MQ has been observed in preclinical settings to elevate NAD+ availability, enhance metabolic flux, and upregulate downstream signaling programs associated with cellular stress responses and energy expenditure (e.g., SIRT1)

Severe allergic reactionssuch as difficulty breathing, rash, or swelling of the face and throatare extremely rare but require immediate medical attention

5-Amino-1MQ was developed as a research tool to selectively block NNMT in vitro and in vivo, primarily by the Watowich group at the University of Texas at Austin

Description 5-Amino-1MQ 5-Amino-1MQ is a small molecule compound that researchers have identified as a selective inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular metabolism and NAD+ salvage pathways

Common mild side effect may include soreness or redness at injection site, mild diarrhea, nausea, headache, and itching