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The AUCCSF/AUCplasma ratio after nasal delivery does not differ from the ratio after intravenous infusion, indicating that hydroxocobalamin enters the CSF via the blood circulation across the blood-brain barrier (BBB)

* Correspondence: Laura Trov [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Mixing vials : Keep BAC water separate

10.1016/S1369-5266(98)80114-3 35 DixonD

Conversely, the removal of the methyl group from lysine and nucleotides requires high energy, and molecular oxygen paired with -KG acts as an electron acceptor for this reaction

In this way, the cell can maintain tight control over protein oxidation