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Microsomal prostaglandin E synthase type 2 (mPGES2) is a glutathione-dependent heme protein, and dithiothreitol dissociates the bound heme to produce active prostaglandin E2 synthase in vitro

Andreeff M , Darzynkiewicz Z, Traganos F, Melamed MR

doi:10.3109/10715762.2010.485989 Diaz Vivancos P, Wolff T, Markovic J, Pallard FV, Foyer CH (2010) A nuclear glutathione cycle within the cell cycle

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Additionally, no significant change was observed in human studies, and the results were insufficient to draw any conclusions [28]