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Rather than directly activating GABA-A receptors, the peptide appears to maintain homeostasis of the entire GABA receptor complex, preventing the desensitization and compensatory changes that produce tolerance and dependence

Furthermore, the expression of SLC7A11 at the PM level was promoted by upregulating Sec24C WT rather than Sec24C MUT (Fig

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The area under the ROC curve was 0.953% and the 95% confidence interval was 0.8721 for the eight identified metabolites that were included in a model predictor (Fig

S-adenosylhomocysteine AHCY is the only enzyme that catalyzes the reversible hydrolysis of SAH into adenosine and homocysteine, thereby maintaining methylation homeostasis within the methionine cycle

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